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Through their simulation, the pair could home in on physical factors that determine whether the fragmented vesicles of the disassembled Golgi form a properly organized structure or give rise to warped and distorted structures.

Their results provide strong additional support for the self-assembly model of Golgi organization.

The calculations were computationally demanding, requiring a week to complete a full simulation, but they were ultimately successful.

We first constructed a physical model of the Golgi based on its stationary state (Fig. This model also reproduced the highly dynamic reassembly process of the mitotic Golgino additional assumptions were necessary.

We think there are lots of possibilities of updating cell biology using physical, mathematical and theoretical sciences, he says.